Suprachoroidal space expansion
Though no significant changes were seen in choroidal thickness in either arm over the 3 months of the study, Dr. Yiu noted there was a trend toward suprachoroidal space expansion in the eyes in the combination group which received the suprachoroidal triamcinolone injections compared with the monotherapy arm (13.4 versus 5.3 μm, respectively) (p = 0.077).
When they examined only eyes in which the suprachoroidal space could be clearly seen on EDI-OCT images at baseline, they found the suprachoroidal expansion was significant (16.2 versus 27.8 μm) (p = 0.033) across months 1 to 3 of the study.
Although IOP increases developed in four eyes that received the combination treatment, two of these had pre-existing glaucoma. The suprachoroidal spaces in these patients did not differ significantly from the others.
Glenn Yiu, MD, PhD
E: [email protected]
This article was reviewed by Dr. Yiu. Dr. Yiu has no financial interest in any aspect of this report.