Future metric needed
He commented on the importance of identifying an objective, easy-to-follow measurement tool for treating diabetic retinopathy. In particular, as new therapies emerge for diabetic retinopathy, an objective and quantifiable metric for gauging treatment response and need for ongoing treatment may be required to facilitate physician decision-making.
“Overall, intravitreal aflibercept resulted in significant improvements in visual acuity and macular edema in this cohort,” Dr. Ehlers explained. “Additional ultra-widefield quantitative parameters showed significant reductions in microaneurysms, especially in the posterior pole, and in leakage and ischemia seen on the ultra-widefield angiography images.
“Quantitative segmentation presents a unique opportunity for potential endpoints and for understanding some of the changes that occur in patients,” he added. “ In addition, higher order assessment of these imaging features, including potential machine learning, may provide new imaging biomarkers to better characterize these common retinal vascular diseases.”