Technology makes great tool, requires extra vigilance with co-existing disease
Though anterior uveitis is associated with myriad conditions, a relatively short list of disorders accounts for the vast majority of cases.
Inhibition plays role in autoimmune-based inflammation; has unique mechanism of action
Improvement in visual acuity, central retinal thickness, vitreous haze reported at 6 months
FA implant effective in lowering recurrence rates through available 6, 12 months of follow-up
Quiescence, steroid-free quiescence achieved in VISUAL III trial
One biologic response modifier has indication for uveitis; several in development to gain FDA approval
Intravitreal triamcinolone acetonide, dexamethasone implant superior for regional treatment of disorder
Punctate inner choroidopathy (PIC) and multifocal choroidopathy (MFC) with panuveitis are different conditions and not part of a spectrum of the same disease.
Palo Alto, CA—Results from SATURN, an exploratory phase 2 study, suggest that sarilumab (Kevzara, Sanofi/Regeneron), a human monoclonal antibody directed against the alpha subunit of the interleukin-6 (IL-6) receptor complex, may be an ef