Perspectives on Retinal Fluid Management in nAMD and DME


Judy Kim, MD and Peter Kaiser, MD discuss the significance of fluid dynamics in nAMD and DME, highlighting the detrimental effects of fluid fluctuations and emphasize the importance of minimizing these fluctuations to achieve better visual outcomes.


Experts discuss the management of neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME) with a focus on fluid management using OCT imaging. They emphasize the importance of distinguishing between different types of fluid accumulation, such as intra-retinal, sub-retinal, and sub-RPE fluid, and its impact on visual acuity outcomes. They highlight findings from studies indicating that intra-retinal fluid is particularly detrimental to visual outcomes in both diseases. Additionally, they discuss the importance of minimizing fluid fluctuations over time to prevent worse visual outcomes and increased fibrosis. The physicians also mention the variability in response to treatment among patients and the need to consider switching treatment agents if necessary, particularly in cases where patients remain wet despite ongoing treatment.

This summary was AI-generated and edited for clarity.

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