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Ophthalmic complications observed in patients taking semaglutide and tirzepatide
The main outcomes were the measurements of the visual acuity and visual field defects.
Successful treatment of RPE65-mediated inherited retinal dystrophy with voretigene neparvovec
Previous research has shown that voretigene neparvovec administered subretinally early in childhood for RPE65-mediated inherited retinal dystrophy achieved encouraging efficacious results.
SeaBeLife announces preclinical efficacy results for SBL03 topical ophthalmic gel
The gel addresses necrotic retinal cell death in dry age-related macular degeneration and geographic atrophy without requiring injections
MACUSTAR receives additional EMA support for AMD clinical study
The scientific outputs from MACUSTAR’s study could impact more than 200 million patients with AMD globally
AI Optics’ portable Sentinel Camera gains FDA 510(k) clearance
The Sentinel Camera aims to address critical gaps in retinal disease screening by offering a portable device that captures high-quality images that require no dilation of the eye.
Harrow launches Harrow Cares program in partnership with Cencora
The program will deliver a range of high-quality access and affordability services for retina specialists.
A study of the 3-year clinical outcomes in geographic atrophy
Among these eyes, 18.9% of eyes developed nAMD within 36 months.
Apellis Pharmaceuticals receives approval of pegcetacoplan (Syfovre) for treatment of geographic atrophy in Australia
The approval of Syfovre makes it the first and only approved treatment for GA in Australia.
Viralgen and Axovia Therapeutics partner to manufacture gene therapy for Bardet-Biedl Syndrome
The companies will work together by using the codon-optimized BBS1 AAV9 vector to minimize the vision loss caused by the genetic defects in the BBS1 gene.
Tyrosine kinase inhibitor: An alternative treatment for non–small-cell lung cancer metastasis to the choroid
Investigators conducted a retrospective review that spanned 10 years with the goals of describing the clinical characteristics of choroidal metastasis in this patient population and report treatment outcomes after targeted therapy compared with conventional radiotherapy and/or chemotherapy.
Researchers identify 'triangle sign' as key diagnostic marker in ocular pathologies
The “Triangle sign” seen on ultrasound is a “distinctive and reliable” ultrasound feature for differentiating total choroidal detachments and suprachoroidal hemorrhages.
10-year data shows progressive visual decline in myopic children and adults
Effects of premature birth on the retina of adults
The investigators found that the premature births to be associated with vascular changes on ocular coherence tomography-angiography.
NeurEYE team leads AI research to detect dementia through retinal imaging
The NeurEYE research team will use millions of eye scans from Scottish optometrists to create the data set.
Clearside Biomedical’s Asia-Pacific Partner, Arctic Vision, receives approval for suprachoroidal treatment for uveitic macular edema in Australia and Singapore
ARCATUS or ARVN001, in Greater China, South Korea, Australia, New Zealand, India and the ASEAN Countries is formally known as XIPERE in the United States and was developed by Clearside Biomedical.
FDA grants fast track designation to N-acetylcysteine amide tablets from Nacuity Pharmaceuticals
The NPI-001 (N-acetylcysteine amide) tablets are a proprietary investigational therapy for the treatment of patients with retinitis pigmentosa.
HELIOS trial: Promising 1-Year results of phase I study for treating NPDR
DRSS stable/improved with OKT-TKI; drug well tolerated
Potential effect of temperature changes on anti-VEGF drugs
Home-stored anti-VEGF drugs face risks from temperature changes, pointing to a need to protect efficacy and avoid dangerous contamination.
PulseSight Therapeutics submits Clinical Trial Authorization for phase I trial of PST-611
The transferrin vectorised therapy is being investigated for use in patients with dry age-related macular degeneration and geographic atrophy
Outlook Therapeutics completes analysis of 12-week safety and efficacy results of NORSE EIGHT
The trial evaluated ONS-5010 in wet age-related macular degeneration patients, and the company plans to resubmit a Biologics License Application in the first quarter of 2025.
Macrophomina phaseolina: An emerging ocular infection in humans
They report a case of endophthalmitis and undertook a literature review to identify previous infections with this pathogen.
Cost-effectiveness of AI pediatric eye screening
Cost among other factors may deter patients from screening, especially in rural and low-resource settings.
Inflammasome Therapeutics announces positive topline 3-month data of K8 implant in patients with GA
In the 5 patients with bilateral geographic atrophy (GA) who received a K8 implant in 1 eye, there was a mean reduction in GA lesion growth of 66% at 3 months.
RhyGaze secures Series A financing of $86 million to further novel gene therapy
The funding will support activities like formal pharmacology and toxicology testing.
EyePoint Pharmaceuticals provides company updates, 2025 milestones for Duravyu
The company's lead product candidate Duravyu (vorolanib intravitreal insert), f/k/a EYP-1901, is anticipating topline data from several clinical trials in 2026.
InflammX Therapeutics enters into option agreement with Bausch + Lomb
InflammX’s pipeline includes an orally dosed therapeutic candidate targeting intermediate age-related macular degeneration.
Positive association between the dietary inflammatory index and non-refractive visual impairment in US patients
Ashvattha Therapeutics secures $50M in financing to advance clinical trials
The new funding will allow the company to complete its ongoing Phase 2 trial of proprietary nanomedicine, migaldendranib, in patients with wet AMD and DME
Samsara Vision announces positive intermediate-term visual and safety outcomes of SING IMT 6 months post-surgery
The retrospective SING IMT study included 35 patients (55 years or older) with late-stage age-related macular degeneration (AMD).
Formycon partners with Teva, Klinge Biopharma for commercialization of aflibercept biosimilar FYB203 (AHZANTIVE)
Previously, Teva was established as the European commercialisation partner of FYB201, Formycon's biosimilar to ranibizumab (Lucentis).